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Hematology is the branch of medicine involving study and treatment of the blood. Hematology tests include tests on the blood cells, hemoglobin, blood proteins, bone marrow, platelets, blood vessels, spleen, and the mechanism of coagulation. These tests can evaluate a variety of blood conditions including infection, anemia, inflammation, hemophilia, blood-clotting disorders, leukemia and the body's response to chemotherapy treatments. The laboratory work that goes into the study of blood is frequently performed by a medical technologist or medical laboratory scientist.
Biochemical tests are most often applied to samples of serum, plasma and urine where levels of specific chemicals are measured and the results compared with those representative of a healthy individual. ... Specialized assays are used to measure the levels of various hormones in the blood. Measurement of blood glucose (sugar) and lipids (fats) are among the commonly performed tests in the biochemistry laboratory. Panels of tests can be used to assess the function of major body organs such as the liver, kidneys and heart. Specialized assays are used to measure the levels of various hormones in the blood. Entire range of biochemistry tests is available in our diagnostic centers.
Clinical pathology supports the diagnosis of disease using laboratory testing of blood and other bodily fluids, tissues, and microscopic evaluation of individual cells.
Clinical pathology includes:
Clinical Microbiology: This encompasses five different sciences. These include bacteriology, virology, parasitology, immunology, and mycology.
Clinical Chemistry: Units under this section include instrumental analysis of blood components, enzymology, toxicology and endocrinology.
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease).
Serological tests may be performed for diagnostic purposes when an infection is suspected, in rheumatic illnesses, and in many other situations, such as checking an individual's blood type. Serology blood tests help to diagnose patients with certain immune deficiencies associated with the lack of antibodies, such as X-linked agammaglobulinemia. In such cases, tests for antibodies will be consistently negative.
Serological methods are diagnostic methods that are used to identify antibodies and antigens in patients sample which is serum and plasma. There are some classical serological methods like Agglutination and Precipitation that are used to identify infectious diseases and human blood grouping typing.
There are several serology techniques that can be used depending on the antibodies being studied. These include: ELISA, agglutination, precipitation, complement-fixation, and fluorescent antibodies and more recently chemiluminescence.
Some serological tests are not limited to blood serum, but can also be performed on other bodily fluids such as semen and saliva, and cerebrospinal fluid (CSF) which may contain antibodies.
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Histopathologists are doctors who work closely with other clinical specialties. They can reach a diagnosis by examining a small piece of tissue from the skin, liver, kidney or other organ. This is called a biopsy.
Histopathologists provide a diagnostic service for cancer; they handle the cells and tissues removed from suspicious 'lumps and bumps', identify the nature of the abnormality and, if malignant, provide information to the clinician about the type of cancer, its grade and, for some cancers, its responsiveness to certain treatments.
Cytogenetics is the study of chromosomal structure, location and function in cells. It includes the study of chromosome number and appearance (karyotyping), the physical location of genes on chromosomes, and chromosomal behaviour in processes such as cell division.
The World Health Organisation (WHO) recognizes immunophenotyping as one of the basic tenets of its Classification system of Haematolymphoid neoplasias. Flow cytometry is a powerful, rapid and convenient technique for the immunophenotypic identification as well as monitoring of many hematopoietic neoplasms.
The technique analyzes the physical and chemical characteristics of particles in a fluid as it passes through at least one laser. Cell components are fluorescently labeled and then excited by the laser to emit light at varying wavelengths. It is routinely used in the diagnosis of health disorders, especially blood cancers.
Uroflowmetry is a simple, diagnostic screening procedure used to calculate the flow rate of urine over time. The test is noninvasive (the skin is not pierced), and may be used to assess bladder and sphincter function.
Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin. Therefore, LC-MS may be applied in a wide range of sectors including biotechnology, environment monitoring, food processing, and pharmaceutical, agrochemical, and cosmetic industries.